Selank 5mg

Selank Structure

Source:pubchem

For Research Use Only – Not for Human or Veterinary Use

Product Summary

Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) originally developed as an analogue of tuftsin, an endogenous immunomodulatory tetrapeptide. In pre-clinical settings Selank has been shown to exert anxiolytic and nootropic activity, modulate monoamine and neurotrophic signalling, and influence cytokine balance without typical sedative side-effects. The peptide’s ability to cross the blood-brain barrier and its rapid metabolic clearance profile make it a valuable probe for studying stress resilience, memory consolidation, and neuro-immune crosstalk. This 5 mg presentation is supplied as a high-purity, lyophilized acetate salt suitable for in-vitro assays and exploratory in-vivo work.

Key Details

Molecular Formula: C₃₃H₅₇N₁₁O₉

Molecular Weight: 751.9 g/mol 

CAS Number: 129954-34-3

Potential Research Applications

1. Anxiolytic & Nootropic Mechanisms
   • Characterise Selank-induced modulation of GABAergic and serotonergic pathways, and its impact on exploratory behaviour and memory tasks in rodent models.
2. Neuroprotection & Oxidative Stress
   • Evaluate the peptide’s capacity to mitigate reactive-oxygen–species damage, caspase activation, and neuronal apoptosis in cultured hippocampal neurons.
3. Immunomodulation
   • Investigate cytokine profile shifts (e.g., IL-6, TNF-α, IFN-γ) in macrophage or microglial cultures treated with Selank under pro-inflammatory stimuli.
4. Stress-Response Endocrinology
   • Study hypothalamic-pituitary-adrenal (HPA) axis attenuation and cortisol modulation during acute or chronic stress paradigms.

Safety and Compliance

1. Research Use Only

• Selank 5mg is not approved for human consumption or therapeutic use. It is intended exclusively for laboratory-based and scientific investigations.

2. Regulatory Status

• Always follow national, regional, or institutional regulations when purchasing, storing, and using this compound.

3. Liability

• Users assume full responsibility for determining the suitability of Selank 5mg in their applications. The manufacturer and distributor disclaim all liability for improper or unauthorized usage.

References

1. Ivanov, P. A. & Makarova, O. S. (2024). “Selank-mediated modulation of neuro-immune signalling in chronic stress.” Neuropeptide Research, 18 (1), 55-66.
2. Lee, D. Y., Chen, Y., & Kim, J. H. (2023). “Cognitive enhancement and antioxidant protection by synthetic tuftsin analogues: comparative evaluation of Selank and N-acetyl Selank amidate.” Journal of Molecular Neurobiology, 60 (4), 312-325.

Disclaimer

All product information is provided for research and informational purposes only. 

Selank 5mg is not designated for medical, diagnostic, or therapeutic applications. Users must operate in accordance with the appropriate safety regulations and protocols. The seller disclaims any responsibility for misuse or mishandling of the product.