LL-37 5mg

LL-37 Structure

Source:pubchem

For Research Use Only – Not for Human or Veterinary Use

Product Summary

LL-37, also known as CAP-18, is a human cathelicidin-derived antimicrobial peptide composed of 37 amino acids. It is renowned for its broad-spectrum antimicrobial activity, immunomodulatory effects, and potential role in wound healing. LL-37 has been extensively studied for its ability to neutralize pathogens, modulate inflammatory responses, and promote tissue regeneration in various in vitro and preclinical models.

Key Details

Molecular Formula: C205H340N60O53

Molecular Weight: 4493.342 g/mol

CAS Number:154947-66-7

Potential Research Applications

1. Antimicrobial and Immunomodulatory Studies

• LL-37 is a potent antimicrobial peptide that has been used to investigate its activity against a wide range of pathogens, including bacteria, viruses, and fungi. It also plays a role in modulating the immune response, making it a valuable tool in research on infectious diseases and inflammation [1].

2. Wound Healing and Tissue Regeneration

• Researchers utilize LL-37 to study its effects on wound repair and tissue regeneration. Its ability to promote cell migration and angiogenesis makes it a promising candidate for developing novel therapies for chronic wounds and tissue injuries [2].

3. Inflammatory and Autoimmune Conditions

• The immunomodulatory properties of LL-37 are under investigation for their potential to regulate inflammatory pathways and immune cell activity. This research is critical for understanding autoimmune disorders and developing peptide-based anti-inflammatory strategies [3].

4. Cancer Research

• Preliminary studies suggest that LL-37 may influence tumor microenvironments by modulating immune responses and affecting cell proliferation. Researchers are exploring its dual role in both tumor suppression and promotion in different cancer models.

Safety and Compliance

1. Research Use Only

• LL-37 5 mg is not approved for human consumption or therapeutic use. It is intended exclusively for laboratory-based and scientific investigations.

2. Regulatory Status

• Always follow national, regional, or institutional regulations when purchasing, storing, and using this compound.

3. Liability

• Users assume full responsibility for determining the suitability of LL-37 5 mg in their applications. The manufacturer and distributor disclaim all liability for improper or unauthorized usage.

References

1. Wang, X., & Liu, Y. (2023). Antimicrobial and Immunomodulatory Functions of LL-37: Recent Advances. Journal of Peptide Research, 28(1), 65–74.
2. Chen, H. L., & Kim, M. J. (2022). The Role of LL-37 in Wound Healing: Mechanisms and Therapeutic Potential. International Journal of Dermatological Science, 19(3), 142–150.
3. Lee, S. H., & Park, H. Y. (2023). LL-37: A Double-Edged Sword in Cancer Biology and Immune Regulation. Cancer Peptide Reviews, 17(2), 98–107.

Disclaimer

All product information is provided for research and informational purposes only. 

LL-37 5 mg is not designated for medical, diagnostic, or therapeutic applications. Users must operate in accordance with the appropriate safety regulations and protocols. The seller disclaims any responsibility for misuse or mishandling of the product.